K. Anderson et al., Quantitative assessment with SPECT imaging of stress injuries of the pars interarticularis and response to bracing, J PED ORTH, 20(1), 2000, pp. 28-33
The evaluation and management of acute spondylolysis remains unclear in par
t because of outcome data that are primarily subjective. The aim of this st
udy was to evaluate and monitor these patients objectively using quantitati
ve single-photon emission computed tomography (SPECT). Thirty-four patients
were so observed clinically between 1987 and 1996 and were studied with an
initial and at least one follow-up SPECT scintigram. initial radiographs a
nd planar bone scans failed to demonstrate the pars lesion in 53 and 19% of
the patients, respectively. The average SPECT ratio before brace treatment
was 1.45. After treatment, this ratio significantly decreased to 1.27 (p =
0.03). A subset of patients remained symptomatic at follow-up. Their reduc
tion in SPECT ratio averaged only 2.8% as compared with 13% for the remaind
er of the patients (p = 0.01). Patients diagnosed and braced in the early,
more active stage of the condition (with greater intensity on SPECT) had mo
re predictable symptom relief. An initial SPECT ratio of >1.5 was associate
d with complete symptom resolution after brace treatment. Patients treated
with activity restriction only (>3 months) before bracing were more likely
to have persistent symptoms and more modest improvement on SPECT (p = 0.01)
. These data, which use SPECT scintigraphy, support prompt treatment with b
race immobilization for acute spondylolysis in children and adolescents.