Hemodynamic profiles during piggyback liver grafts using arterial or portal revascularization

Background: The order of revascularization in human liver grafts is still d iscussed. This study tries to answer this question in terms of hemodynamic data. Study Design: Fifty-nine patients were randomized in this study to compare hemodynamic data just before and 15 minutes after revascularization of live r grafts in relation to first hepatic artery (n = 29) or first portal vein (n = 30) revascularization procedure. Results: Hemodynamic variations were significantly greater in the portal ve in group than in the hepatic artery group in terms of mean arterial pressur e, cardiac index, central venous pressure, pulmonary capillary pressure, an d systemic vascular resistance. The latter decreased from 741.8 +/- 390.3 t o 659.9 +/- 411.1 dynes/cm(5) (NS) in the hepatic artery group versus 807.7 +?- 336.7 to 439.7 +/- 215 dynes/cm(5) (p < 0.05) in the portal vein group . Clinical results and postoperative complications, graft characteristics, patient survival, and graft survival were not significantly different betwe en the groups. Conclusions: Initial arterial revascularization of the liver graft leads to a more stable hemodynamic profile during revascularization of the liver gr aft after vascular unclamping. This technique is always feasible and has be come our reference procedure. (J Am Coll Surg 2000;190:89-93. (C) 2000 by t he American College of Surgeons).