Binding of small phosphorylated chromatin peptides to DNA

Authors
Cardellini, E Adami, F Gianfranceschi, GL
Citation
E. Cardellini et al., Binding of small phosphorylated chromatin peptides to DNA, MOL BIOL RP, 26(4), 1999, pp. 249-253
Citations number
22
Categorie Soggetti
Molecular Biology & Genetics
Journal title
MOLECULAR BIOLOGY REPORTS
ISSN journal
03014851 → ACNP
Volume
26
Issue
4
Year of publication
1999
Pages
249 - 253
Database
ISI
SICI code
0301-4851(199912)26:4<249:BOSPCP>2.0.ZU;2-4
Abstract
Low-molecular-weight peptides involved in gene expression and cell growth h ave been isolated from DNA preparation from eukaryotic cells. After phospho rylation with protein kinase CKII (pCKII) these peptides are able to bind t o DNA in presence of divalent cations and salt/ethanol. This finding may ex plain the mechanism by which the peptides exert their activity.