This paper describes some basic processes involved when a DNA molecule face
s a pore and gets through. In the simple case considered here, the only dri
ving force is a concentration difference between DNA outside and inside. Fo
r plausible conditions, the transfection time (the time required to force o
ne molecule in) is expected to be reasonably short. (C) 1999 Elsevier Scien
ce B.V. All rights reserved.