Citation
Kk. Lee et al., Bioactive indole alkaloids from the bark of Uncaria guianensis, PLANTA MED, 65(8), 1999, pp. 759-760
Citations number
15
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943
→ ACNP
Volume
65
Issue
8
Year of publication
1999
Pages
759 - 760
Database
ISI
SICI code
0032-0943(199912)65:8<759:BIAFTB>2.0.ZU;2-D
Abstract
Bioassay-guided fractionation of the EtOH extract of the bark of Uncario gu
ianensis (Aubl.) Gmel (Rubiaceae) using a yeast-based assay for DNA-damagin
g agents has furnished the two weakly but selectively active indole alkaloi
ds uncarine C (1) and uncarine E (2) as the major bioactive constituents in
this assay.