Fifteen iatrogenic femoral pseudoaneurysms failed ultrasonography (US)-guid
ed compression treatments. Despite concomitant antiplatelet or anticoagulat
ion treatment, the 15 pseudoaneurysms were successfully and definitively tr
eated without complication with US-guided thrombin injection. Results in th
is preliminary study suggest US-guided thrombin injection is a safe, expedi
tious, low-cost, and comfortable definitive treatment for femoral pseudoane
urysms that has advantages over both US-guided compression and open surgica
l repair.