Intramolecular cyclization of ortho-(cyclohex-2-enyl)anilines. Modified synthesis of ellipticine

Authors
Mustafin, AG Khalilov, IN Ismagilov, RR Baimetov, ZM Spirikhin, LV Abdrakhmanov, IB Tolstikov, GA
Citation
Ag. Mustafin et al., Intramolecular cyclization of ortho-(cyclohex-2-enyl)anilines. Modified synthesis of ellipticine, RUSS CHEM B, 48(11), 1999, pp. 2121-2126
Citations number
20
Categorie Soggetti
Chemistry
Journal title
RUSSIAN CHEMICAL BULLETIN
ISSN journal
10665285 → ACNP
Volume
48
Issue
11
Year of publication
1999
Pages
2121 - 2126
Database
ISI
SICI code
1066-5285(199911)48:11<2121:ICOOMS>2.0.ZU;2-0
Abstract
It was found that the reactions of arylamines with 3-bromocyclohexene affor ded hydrocarbazole compounds in 64-78% yields. A modified procedure for the synthesis of antitumor alkaloid ellipticine was proposed.