G. Gambassi et al., Management of heart failure among very old persons living in long-term care: Has the voice of trials spread?, AM HEART J, 139(1), 2000, pp. 85-93
Citations number
49
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Background increasing prevalence, use of health services, and number of dea
ths have made congestive heart failure (CHF) a new epidemic in the United S
tates. Yet there are no adequate data to guide treatment of the more typica
l and complex cases of patients who are very old and frail.
Methods Using the SAGE database, we studied the cases of 86,094 patients wi
th CHF admitted to any of the 1492 long-term care facilities of 5 states fr
om 1992 through 1996. We described their clinical and functional characteri
stics and their pharmacologic treatment to verify agreement with widely app
roved guidelines. We evaluated age- and sex-related differences, and we det
ermined predictors of receiving an angiotensin-converting enzyme (ACE) inhi
bitor by developing a multiple logistic regression model.
Results The mean age of the population was 84.9 +/- 8 years. Eighty percent
of the patients 85 years of age or older were women. More than two thirds
of patients underwent frequent hospitalizations related to CHF in the year
preceding admission to a long-term care facility. Coronary heart disease an
d hypertension were the most common causes. Half of the patients received d
igoxin and 45% a diuretic, regardless of background cardiovascular comorbid
ities. Only 25% of patients had a prescription for ACE inhibitors. The pres
ence of cardiovascular comorbidity, already being a recipient of a large nu
mber of medications, a previous hospitalization for CHF, and admission to t
he facility in recent years were associated with an increased likelihood of
receiving an ACE inhibitor. The presence of severe physical limitation was
inversely related to use of ACE inhibitors, as were a series of organizati
onal factors related to the Facilities.
Conclusions Patients in long-term care who have CHF little resemble to thos
e enrolled in randomized trials. This circumstance may explain, at least in
part, the divergence from pharmacologic management consensus guidelines. Y
et the prescription of ACE inhibitors varies significantly across facilitie
s and depends on organizational characteristics.