Secondary (AA-type) amyloidosis in patients with polymyalgia rheumatica

Authors
Escriba, A Morales, E Albizua, E Herrero, JC Ortuno, T Carreno, A Dominguez-Gil, B Praga, M
Citation
A. Escriba et al., Secondary (AA-type) amyloidosis in patients with polymyalgia rheumatica, AM J KIDNEY, 35(1), 2000, pp. 137-140
Citations number
25
Categorie Soggetti
Urology & Nephrology
Journal title
AMERICAN JOURNAL OF KIDNEY DISEASES
ISSN journal
02726386 → ACNP
Volume
35
Issue
1
Year of publication
2000
Pages
137 - 140
Database
ISI
SICI code
0272-6386(200001)35:1<137:S(AIPW>2.0.ZU;2-7
Abstract
Several cases of systemic amyloidosis associated with polymyalgia rheumatic a (PMR) or giant-cell arteritis (GCA) have been described. Nevertheless, th e type of amyloid deposit has not been characterized in most of them. Here we report on two patients with PMR (one with associated GCA) who developed nephrotic syndrome and end-stage renal failure caused by massive amyloid de position. Immunohistochemical analysis showed that the amyloid deposits wer e of AA type (secondary amyloidosis) in both cases. (C) 2000 by the Nationa l Kidney Foundation, Inc.