Clinical and magnetic resonance imaging findings in chronic sensory ganglionopathies

Twenty-two of 29 patients with chronic sensory ataxic neuropathy showed T2- weighted magnetic resonance imaging high signal intensity in the posterior columns of the cervical spine. T2 changes reflected the degeneration of cen tral sensory projections and localized the disease process to T-shaped dors al root ganglion neurons. No similar abnormalities were found in sensory an d sensorimotor length-dependent axonal neuropathy patients. Spinal cord mag netic resonance imaging is a useful tool to support the clinical diagnosis of primary ganglionopathy.