OBJECTIVE: To evaluate the use of calcium supplementation in the treatment
of premenstrual syndrome.
DATA SOURCES: Clinical literature accessed through MEDLINE (from January 19
67 to September 1999). Key search terms included calcium PMS, and premenstr
ual.
DATA SYNTHESIS: UP to 50% of women experience some form of premenstrual syn
drome. An evaluation of studies focusing on calcium in the management of pr
emenstrual symptoms was conducted.
CONCLUSIONS: Calcium supplementation of 1201-1600 mg/d, unless contraindica
ted, should be considered a sound treatment option in women who experience
premenstrual syndrome. The supplemental dose of calcium can be adjusted dow
nward in the few patients who routinely consume large quantities of calcium
in their diet.