Hair and blood as substrates for screening children for lead poisoning

Citation
E. Esteban et al., Hair and blood as substrates for screening children for lead poisoning, ARCH ENV HE, 54(6), 1999, pp. 436-440
Citations number
13
Categorie Soggetti
Environment/Ecology,"Pharmacology & Toxicology
Journal title
ARCHIVES OF ENVIRONMENTAL HEALTH
ISSN journal
00039896 → ACNP
Volume
54
Issue
6
Year of publication
1999
Pages
436 - 440
Database
ISI
SICI code
0003-9896(199911/12)54:6<436:HABASF>2.0.ZU;2-0
Abstract
In Russia, hair, rather than blood, is usually used as a substrate for scre ening children for lead poisoning. We attempted to gauge the accuracy of th is method by comparing these two methods. The evaluation was done in Sarato v, Russia. We collected hair and blood samples from 189 children who attend ed 11 kindergartens. Their mean blood lead concentration was 9.8 mu g/dl (r ange = 3.1-35.7 mu g/dl), and their mean hair lead concentration was 7.2 mu g/g (range = 1.0-7.2 mu g/g [i.e., 1.0 being the lowest detectable limit]) . Hair lead concentration as a screening method had 57% sensitivity and res ulted in 18% of the children being classified as false-negatives. We conclu de, therefore, that measuring hair lead concentration is not an adequate me thod with which to screen children for lead poisoning.