Characterization of a new ATP-binding cassette transporter in Trypanosoma cruzi associated to a L1Tc retrotransposon

Authors
Torres, C Barreiro, L Dallagiovanna, B Gamarro, F Castanys, S
Citation
C. Torres et al., Characterization of a new ATP-binding cassette transporter in Trypanosoma cruzi associated to a L1Tc retrotransposon, BBA-GENE ST, 1489(2-3), 1999, pp. 428-432
Citations number
25
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1489
Issue
2-3
Year of publication
1999
Pages
428 - 432
Database
ISI
SICI code
0167-4781(199912)1489:2-3<428:COANAC>2.0.ZU;2-L
Abstract
We have characterized the tcpgp1-like gene of Trypanosoma cruzi, a new ATP- binding cassette (ABC) transporter. tcpgp1 codes for a 1035 amino acid prot ein with a considerable homology to LtpgpA of Leishmania. Tcpgp1 lacks the conserved sequences corresponding to the second nucleotide-binding domain o f other ABC transporters due to the insertion of the L1Tc non-LTR retrotran sposon. (C) 1999 Elsevier Science B.V. All rights reserved.