The presence of an endogenous endo-D-arabinase in Mycobacterium smegmatis and characterization of its oligoarabinoside product

Authors
Xin, Y Huang, YG McNeil, MR
Citation
Y. Xin et al., The presence of an endogenous endo-D-arabinase in Mycobacterium smegmatis and characterization of its oligoarabinoside product, BBA-GEN SUB, 1473(2-3), 1999, pp. 267-271
Citations number
13
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
ISSN journal
03044165 → ACNP
Volume
1473
Issue
2-3
Year of publication
1999
Pages
267 - 271
Database
ISI
SICI code
0304-4165(199912)1473:2-3<267:TPOAEE>2.0.ZU;2-X
Abstract
Endogenous mycobacterial endo-D-arabinase activity, which degrades cell wal l polysaccharide arabinogalactan, was found in Mycobacterium smegmatis. The arabinan product contains 20-30 arabinosyl residues but no galactofuranosy l residues. Recognition of this endogenous activity results in the possibil ity of developing antituberculosis drugs that do not require bacterial grow th for activity. (C) 1999 Elsevier Science B.V. All rights reserved.