K. Khunti et al., Diagnosis of patients with chronic heart failure in primary care: usefulness of history, examination, and investigations, BR J GEN PR, 50(450), 2000, pp. 50-54
Chronic heart failure is a common clinical syndrome that may have different
causes. Its incidence and prevalence are predicted to rise substantially o
ver the next 10 years. There are therefore major consequences for resource
provision, especially in primary care, where most patients are managed. Chr
onic heart failure is a serious condition with high morbidity and mortality
. There is good evidence to show that treatment with angiotensin-converting
enzyme (ACE) inhibitors in patients with left ventricular systolic dysfunc
tion improves symptoms and signs, slows progression of heart failure, reduc
es hospitalisation rates, and improves survival. Despite this evidence, pri
mary care studies show that patients with heart failure are incorrectly dia
gnosed and inadequately treated. Most patients present in general practice,
and because effective treatment relies on a correct diagnosis, this is a k
ey step in the appropriate management of heart failure. The aim of this pap
er is to review the evidence about the usefulness of signs, symptoms, and i
nvestigations in diagnosing heart failure in primary care. To identify rele
vant studies for this review, four strategies were used: a MEDLINE search f
rom 1993 to January 1998 using the diagnosis search filter; a MEDLINE searc
h from 1993 to January 1998 using the guideline search filter to locate pub
lished heart failure guidelines; a search for review articles in the Cochra
ne Library; and a check of references in the studies identified. The search
terms included MeSH terms and the keywords 'heart failure' and 'diagnosis:
All searches were limited to humans and English language articles. Studies
were included in this review on the basis of quality and relevance to prim
ary care. The review shows that symptoms and signs are important because th
ey alert clinicians to the possibility of heart failure as a diagnosis. How
ever, they are not sufficiently specific for confirming left ventricular sy
stolic dysfunction. From the evidence available, a patient with suspected h
eart failure must have objective tests to confirm the diagnosis. These shou
ld include an electrocardiogram and, ideally, an echocardiogram. Further re
search is also needed on the usefulness of signs and symptoms in primary ca
re, as most studies of heart failure have been conducted in secondary care.