PROTEASE INHIBITORS AND UROLITHIASIS

Purpose: We discuss the specific urological abnormalities associated w ith protease inhibitor therapy. Materials and Methods: We report on a human immunodeficiency virus positive patient who was on protease inhi bitor therapy and presented with renal colic. Results: The stone passe d spontaneously. Stone analysis was not consistent with any known comp osition of urinary calculus. Conclusions: The positive effects of prot ease inhibitors in human immunodeficiency virus positive patients mand ate that the urological community become familiar with these drugs and the specific urological complications as the use of these drugs becom es widespread.