Haematological disease in siblings with Rothmund-Thomson syndrome

Authors
Porter, WM Hardman, CM Abdalla, SH Powles, AV
Citation
Wm. Porter et al., Haematological disease in siblings with Rothmund-Thomson syndrome, CLIN EXP D, 24(6), 1999, pp. 452-454
Citations number
10
Categorie Soggetti
Dermatology
Journal title
CLINICAL AND EXPERIMENTAL DERMATOLOGY
ISSN journal
03076938 → ACNP
Volume
24
Issue
6
Year of publication
1999
Pages
452 - 454
Database
ISI
SICI code
0307-6938(199911)24:6<452:HDISWR>2.0.ZU;2-M
Abstract
We report two siblings with Rothmund-Thomson syndrome (RTS); the older sist er died of acute myeloblastic leukaemia and the younger sister has a slowly progressive leucopenia. Her prognosis is guarded in view of the increased incidence of neoplasms in this condition. More than 200 cases of RTS have n ow been reported worldwide.(1) This is the first report of siblings with ha ematological disease and RTS.