Development, formulation, and effectiveness testing of a silicone-based barrier-type hand cream

We report the development, design, and results of effectiveness and accepta bility testing of a hydrating, nutritive, barrier-type hand cream designed for severely damaged skin (including skin damaged by dermatological problem s). We tested different silicone derivatives and a water-in-oil (W/O) silic one emulsifier to produce organoleptic qualities that would increase consum er acceptance of this type of W/O emulsion. Pharmacotechnical and effective ness tests were done to check the stability and preservation of the formula s, their usefulness in improving dry skin, and acceptance by users. The res ults of pharmacotechnical testing were optimal. Although no active principl e aimed specifically at dermatological problems was present in the final fo rmulas, users reported notable subjective improvements in cracking and scal ing.