THE COMPARATIVE ROLE OF CONSANGUINITY IN INFANT AND CHILDHOOD MORTALITY IN PAKISTAN

Citation
Jc. Grant et Ah. Bittles, THE COMPARATIVE ROLE OF CONSANGUINITY IN INFANT AND CHILDHOOD MORTALITY IN PAKISTAN, Annals of Human Genetics, 61, 1997, pp. 143-149
Citations number
21
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00034800
Volume
61
Year of publication
1997
Part
2
Pages
143 - 149
Database
ISI
SICI code
0003-4800(1997)61:<143:TCROCI>2.0.ZU;2-T
Abstract
As part of the 1990/1991 Pakistan Demographic and Health Survey, data were collected on the outcome of 26408 births to 6611 women, with mort ality rates investigated at specific age intervals during the first 5 years of life. Bivariate and multivariate logistic regression analyses were employed to examine the comparative roles of consanguineous marr iage and a number of demographic and socioeconomic factors, including the sex of the child, maternal age, maternal education, birth interval and birth order, as determinants of early death. The results indicate that, even after controlling for these non-genetic variables, inbreed ing at the level of first cousin exerted a significant adverse effect on survival in four of the five age intervals examined, neonatal, post -neonatal, infant and under 5 years.