Selective oestrogen receptor modulation: Molecular pharmacology for the millennium (Reprinted from Eur J Cancer, vol 35, pg 1974-1985, 1999)

Authors
Levenson, AS Jordan, VC
Citation
As. Levenson et Vc. Jordan, Selective oestrogen receptor modulation: Molecular pharmacology for the millennium (Reprinted from Eur J Cancer, vol 35, pg 1974-1985, 1999), EUR J CANC, 35(14), 1999, pp. 1974-1985
Citations number
134
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
EUROPEAN JOURNAL OF CANCER
ISSN journal
09598049 → ACNP
Volume
35
Issue
14
Year of publication
1999
Pages
1974 - 1985
Database
ISI
SICI code
0959-8049(199912)35:14<1974:SORMMP>2.0.ZU;2-F
Abstract
Knowledge of the mechanism of action and pharmacology of tamoxifen and ralo xifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There i s now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors. (C) 1999 Elsevier Science Ltd. All rights reserved.