Iris fluorescein angiography and iris indocyanine green videoangiography in pseudoexfoliation syndrome

Background. Precise evaluation of the iris vascular pattern in pseudoexfoli ation syndrome (PXS) may be difficult with iris fluorescein angiography (IF A) because of the frequent presence of a heavily pigmented iris and conspic uous late leakage. However, iris indocyanine green videoangiography (IICGV) can precisely visualize details of the iris vascular pattern. This study a nalyzed the utility of IICGV in detecting microvascular changes in PXS and compared these findings with those of IFA. Methods. Twenty-eight patients with PXS in both eyes underwent an ophthalmi c examination including IFA and IICGV. IICGV was done with the IMAGEnet sys tem H1024. Results. IICGV gave better visualization of iris hypoperfusion and anastomo tic vessels whereas iris microneovascularisation was far more clearly visib le on IFA. IICGV also detected iris pigment epithelium defects. Conclusions. IICGV can be considered a useful fool for evaluation of the ir is vascular pattern in PXS. Iris hypoperfusion did not appear to contribute to the development of iris microvascular changes.