M. Antopolsky et A. Azhayev, Stepwise solid-phase synthesis of peptide-oligonucleotide conjugates on new solid supports, HELV CHIM A, 82(12), 1999, pp. 2130-2140
Several peptide-oligonucleotide and peptide-(oligonucleotide phosphorothioa
te) conjugates were synthesized on new solid supports. These supports are d
esigned to link the 3'-terminus of an oligonucleotide to the C-end of a pep
tide via a phosphodiester or phosphorothioate bond in the process of stepwi
se solid-phase assembly.