LUPANE TRITERPENOID GLYCOSYL ESTERS FROM LEAVES OF ACANTHOPANAX-DIVARICATUS

Further investigation of the leaves of Acanthopanax divaricatus gave t wo analogues of chiisanoside, which is a lupane triterpenoid oligoglyc osyl ester. The structures were established as 28-O-alpha-L-rhamnopyra nosyl(1 --> 4)-beta-D-glucopyranosyl( 1 --> 6)beta-D-glucopyranosyl es ters of 1 beta,11 alpha-dihydroxy-3-oxo-lup-20(29)-en-28-oic acid and 1(R),11 alpha,22 ydroxy-3,4-seco-lupa-4(23),20(29)-diene-3,28-dioic ac id 3,11 alpha-lactone based on chemical and spectroscopic evidence. In biosynthetic terms, one is the precursor of chiisanoside and the othe r is an oxygenated derivative chiisanoside. (C) 1997 Published by Else vier Science Ltd.