Synthesis of O,O-diaryl O-n-propyl phosphorothionates and their fungitoxicity against Rhizoctonia solani and Sclerotium rolfsii

Authors
Patra, D Gupta, RL
Citation
D. Patra et Rl. Gupta, Synthesis of O,O-diaryl O-n-propyl phosphorothionates and their fungitoxicity against Rhizoctonia solani and Sclerotium rolfsii, I J CHEM B, 38(9), 1999, pp. 1086-1089
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
38
Issue
9
Year of publication
1999
Pages
1086 - 1089
Database
ISI
SICI code
0376-4699(199909)38:9<1086:SOOOPA>2.0.ZU;2-O
Abstract
Twenty new O,O-diaryl O-n-propyl phosphorothionates 4 have been prepared by condensing O-n-propyl phosphorodichloridothioate with substituted phenols and tested in vitro for fungitoxicity against Rhizoctonia sola,li and Scler otium rolfsii. The compounds O,O-di(3-methylphenyl) O-n-propyl phosphorothi onate 4c against R. solani (ED50=0.229 mg mL(-1)) and O,O-di(2,3-dimethylph enyl) O-n-propyl phosphorothionate 4m against S. rolfsii (ED50=0.275 mg mL( -1)) show the highest activity. Important generalisations on structure-acti vity relationships in this series are being made out based on the fungitoxi city data.