One pot synthesis of novel 5,11-dioxo-6-methyl-5,9,10,11-tetrahydro-8H-naphth-[2,3 : 1,2]pyrrolizine and its 9-acetoxy analogue

Authors
Gadaginamath, GS Kavali, RR Patil, SA Shyadligeri, AS
Citation
Gs. Gadaginamath et al., One pot synthesis of novel 5,11-dioxo-6-methyl-5,9,10,11-tetrahydro-8H-naphth-[2,3 : 1,2]pyrrolizine and its 9-acetoxy analogue, I J CHEM B, 38(9), 1999, pp. 1123-1125
Citations number
9
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
38
Issue
9
Year of publication
1999
Pages
1123 - 1125
Database
ISI
SICI code
0376-4699(199909)38:9<1123:OPSON5>2.0.ZU;2-L
Abstract
5,11-dioxo-6-methyl-5,9,10,11-tetrahydro-8H-naphth[2,3 : 1,2]-pyrrolizine 5 a and its 9-acetoxy analogue 5b are prepared in a one-flask procedure by th e reaction of L-proline 1a or 4-hydroxy-L-proline 1b with refluxing acetic anhydride and olefinic dipolarophile 1,4-naphthoquinone 4.