Selective conversion of nitriles to amides by Amberlyst A-26 supported hydroperoxide

Authors
Lakouraj, MM Bahrami, K
Citation
Mm. Lakouraj et K. Bahrami, Selective conversion of nitriles to amides by Amberlyst A-26 supported hydroperoxide, I J CHEM B, 38(8), 1999, pp. 974-975
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
38
Issue
8
Year of publication
1999
Pages
974 - 975
Database
ISI
SICI code
0376-4699(199908)38:8<974:SCONTA>2.0.ZU;2-L
Abstract
A mild, efficient and selective conversion of nitriles to amides is achieve d by employing Amberlyst A-26 supported hydroperoxide, which is prepared in situ from hydrogen peroxide and Amberlyst A-26 (OH- form). Nitriles and di nitriles are transformed to their corresponding amides and diamides, respec tively. Reactions proceed within 0.5-5 hr upon addition of a catalytic amou nt of Amberlyst A 26(OH-) to a methanolic solution of nitrile and hydrogen peroxide (35%), at room temperature.