FULVINOL, A NEW LONG-CHAIN DIACETYLENIC METABOLITE FROM THE SPONGE RENIERA-FULVA

Authors
ORTEGA MJ ZUBIA E CARBALLO JL SALVA J
Citation
Mj. Ortega et al., FULVINOL, A NEW LONG-CHAIN DIACETYLENIC METABOLITE FROM THE SPONGE RENIERA-FULVA, Journal of natural products, 59(11), 1996, pp. 1069-1071
Citations number
20
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
11
Year of publication
1996
Pages
1069 - 1071
Database
ISI
SICI code
0163-3864(1996)59:11<1069:FANLDM>2.0.ZU;2-G
Abstract
The sponge Reniera fulva from Algeciras Bay, Spain, contains, in addit ion to the five acetylenic compounds described previously, a new long- chain acetylene named fulvinol (1). Its highly symmetric structure was elucidated by interpretation of spectral data, and its absolute confi guration was established using the Mosher method. Fulvinol (1) exhibit ed cytotoxicity against four tumor cell lines (ED(50) = 1 mu g/mL).