Objective. To study the impact of the cost of pharmaceuticals on physi
cians' decisions about drug prescription. Design. A simulation protoco
l for the treatment of two patients, one with mild and the other with
a severe form of urinary tract infection (UTI), was designed. Thirty f
amily physicians in outpatient clinics and 30 physicians in the intern
al medicine wards of a Community Hospital participated in the project.
They had to prescribe treatment for the patients twice: at phase I, w
hen the drug cost was unknown, and at phase II, after 2 months, when t
he price of the drugs was brought to their attention. The physicians s
elected the medication from a list of drugs commonly used for the trea
tment of UTIs. Results. Analysis of the findings indicates that an awa
reness of drug costs affects prescription decisions among physicians i
n hospital wards, whereas family physicians showed a preference for le
ss expensive drugs even before they were informed about drug costs. An
extrapolation of the results shows that knowledge about the cost of t
he drugs usually administered for treatment of UTI, could save at leas
t IS 112883 ($34207) a month to Kupat Holim Klalit (KHK) the health in
surance institution to which the outpatient clinics and the hospital b
elong. Conclusions. When economic aspects of healthcare are considered
, information on drug costs may be an important factor in physicians'
decision-making processes and for saving pharmaceutical expenses.