H. Hawighorst et al., Evaluation of angiogenesis and perfusion of bone marrow lesions: Role of semiquantitative and quantitative dynamic MRI, J MAGN R I, 10(3), 1999, pp. 286-294
Magnetic resonance imaging (MRI) is a noninvasive technique that complement
s computed tomography (CT), conventional X-ray, and bone marrow biopsies by
sampling a large volume of musculoskeletal bone and providing information
that aids the diagnosis, staging, and follow-up of various lesions. Althoug
h less sensitive to the mineral components of bones, the MRI appearance of
physiologic bone marrow is mainly a reflection of the relative amounts of r
ed marrow, yellow marrow, and trabecular bone. Therefore, use of T1-and T2-
weighted MR sequences with or without fat suppression currently remains the
most common approach to musculoskeletal bone lesion imaging, An additional
imaging strategy to characterize various bone lesions is the application o
f contrast-enhanced dynamic MRI, This article examines semiquantitative and
quantitative dynamic imaging, evaluation, and postprocessing techniques in
various benign and malignant musculoskeletal lesions. Practical guidelines
for performing a dynamic contrast-enhanced MR examination are proposed. (C
) 1999 Wiley-Liss, Inc.