Evaluation of angiogenesis and perfusion of bone marrow lesions: Role of semiquantitative and quantitative dynamic MRI

Citation
H. Hawighorst et al., Evaluation of angiogenesis and perfusion of bone marrow lesions: Role of semiquantitative and quantitative dynamic MRI, J MAGN R I, 10(3), 1999, pp. 286-294
Citations number
38
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
ISSN journal
10531807 → ACNP
Volume
10
Issue
3
Year of publication
1999
Pages
286 - 294
Database
ISI
SICI code
1053-1807(199909)10:3<286:EOAAPO>2.0.ZU;2-D
Abstract
Magnetic resonance imaging (MRI) is a noninvasive technique that complement s computed tomography (CT), conventional X-ray, and bone marrow biopsies by sampling a large volume of musculoskeletal bone and providing information that aids the diagnosis, staging, and follow-up of various lesions. Althoug h less sensitive to the mineral components of bones, the MRI appearance of physiologic bone marrow is mainly a reflection of the relative amounts of r ed marrow, yellow marrow, and trabecular bone. Therefore, use of T1-and T2- weighted MR sequences with or without fat suppression currently remains the most common approach to musculoskeletal bone lesion imaging, An additional imaging strategy to characterize various bone lesions is the application o f contrast-enhanced dynamic MRI, This article examines semiquantitative and quantitative dynamic imaging, evaluation, and postprocessing techniques in various benign and malignant musculoskeletal lesions. Practical guidelines for performing a dynamic contrast-enhanced MR examination are proposed. (C ) 1999 Wiley-Liss, Inc.