Sphingomonads involved in the microbial degradation of xenobiotic polymers
are introduced. The metabolism of polyethylene glycol was the primary focus
of the study. Several others, Including polyvinyl alcohol, polyethylene an
d polyaspartate were also studied. It is suggested that these xenobiotic po
lymers are metabolized by intracellular enzymes located in the periplasmic
space or bound to membranes, indicating that transport of these polymers th
rough outer membranes is requisite for their metabolism. Involvement of spe
cific membrane structures of sphingomonads such as unusual sphingolipids is
suggested for membrane transport of xenobiotic compounds, especially hydro
phobic materials.