This study examines the precision required in the timing of muscle activati
ons and projectile release to hit a target of 20 cm in diameter oriented ho
rizontally either 6 or 8 m away. Over-arm throws, constrained to the sagitt
al plane, were simulated using a muscle-actuated, two-segment model represe
nting the forearm and hand plus projectile. The parameters defining the mod
eled muscles and the anthropometry were specific to two male subjects. An o
bjective function specified that throws must be both fast and accurate. Onc
e an optimal solution had been found, the sensitivity of these timings was
investigated. The times of activation or release were changed and the simul
ation model re-run with the new timings, and it was determined whether the
projectile would still have struck the target. For one set of simulations,
to hit the target at 8 m, the optimal throw was achieved with a time delay
between the onset of wrist activation and elbow extensor activation [Proxim
al-distal (PD) delay] of 49 ms and a release time of 83.4 ms. At this optim
al point in the solution space, the launch window was 1.2 ms (assuming the
original PD delay). The launch window was the time available within which t
he projectile must be released and still strike the target. The window duri
ng which the wrist flexors could be activated was 10.41 ms (assuming the pr
ojectile was released at the pre-planned optimal time). The control scheme
which required the least timing precision had a PD delay of 56 ms and a rel
ease time of 89.4 ms. Errors in timing could occur in activation and releas
e simultaneously under this scheme, the timing windows were 4 ms in PD dela
y and 2.4 ms in release. Similar results were found for a second set of sim
ulations. These simulations revealed the precise timings required in muscle
activations and release required for fast accurate throws. (C) 1999 Academ
ic Press.