Nk. Henry et al., Antimicrobial therapy for infants and children: Guidelines for the inpatient and outpatient practice of pediatric infectious diseases, MAYO CLIN P, 75(1), 2000, pp. 86-97
Citations number
70
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
In this article, we discuss antimicrobial regimens for both outpatient and
inpatient use in infants and children. substantial number of pediatric pati
ent visits annually result in the prescribing of antimicrobial drugs, The e
mergence of bacteria resistant to commonly used antimicrobial agents is a g
rowing concern. Information on newer drugs such as meropenem, which is acti
ve against penicillin-resistant Streptococcus pneumoniae and gram-negative
bacilli, and cefepime, which has activity against gramnegative bacilli incl
uding Pseudomonas aeruginosa and against gram-positive cocci is also presen
ted. Management of patients with congenital or acquired immunodeficiencies
continues to be challenging in regard to the use of antimicrobial drugs to
treat various fungal and viral infections. New formulations of older drugs
such as aerosolized tobramycin and amphotericin B lipid complex are availab
le. New antiviral agents have been approved, most of which are antiretrovir
al agents. Childhood tuberculosis is an ongoing concern, and regimens to tr
eat Mycobacterium tuberculosis in children are discussed.