Sa. Cooper, HIGH PREVALENCE OF DEMENTIA AMONG PEOPLE WITH LEARNING-DISABILITIES NOT ATTRIBUTABLE TO DOWNS-SYNDROME, Psychological medicine, 27(3), 1997, pp. 609-616
Background. For many years, it has been known that dementia can occur
in people with learning disabilities, but there have been few research
studies. Studies that do quote rates for dementia show these to be hi
gh, but this important fact has received remarkably little attention.
Method. Comprehensive psychiatric and medical assessments were underta
ken on the whole population (ascertained as far as is possible) of peo
ple with learning disabilities aged 65 years and over living in Leices
tershire, UK (N = 134), in order to ascertain rates of DCR defined dem
entia, and associated factors. Results. Dementia was diagnosed in 21.6
%, against an expected prevalence of 57 %, for a group with this age
structure. The rate of dementia increased in successive age cohorts: 1
5.6 % aged 65-74 years; 23.5 % aged 65-84 years; and 70.0 % aged 85-94
years. People with dementia tended to be older, female, with more poo
rly controlled epilepsy, a larger number of additional physical disord
ers, less likely to be smokers and had lower adaptive behaviour scores
than did the elderly people without dementia. They were more likely t
o live in health service accommodation. Conclusions. Dementia occurs a
t a much higher rate among elderly people with learning disabilities t
han it does among the general population; this is independent of the a
ssociation between dementia and Down's syndrome. Whether this relates
aetiologically to genetics, lack of brain 'reserve' or history of brai
n damage is yet to be determined.