We conducted a serological survey for Toxoplasma gondii in 121 Amerindians
of the Guajibo ethnic group, 4 to 45 years of age, inhabiting Amazonas Stat
e, in the Venezuelan rain forest. The overall prevalence was 88%. Pattern o
f prevalence and antibody titres were compatible with constant transmission
. Sex differences in antibody prevalence were not detected but antibody tit
res were significantly higher in females. The study is consistent with the
presence of risk factors, which favour a frequent exposure of these Amerind
ians to T. gondii since childhood.