Estrogen and progesterone receptor negative T11 vertebral hemangioma presenting as a postpartum compression fracture: Case report and management

Citation
Th. Schwartz et al., Estrogen and progesterone receptor negative T11 vertebral hemangioma presenting as a postpartum compression fracture: Case report and management, NEUROSURGER, 46(1), 2000, pp. 218-221
Citations number
38
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROSURGERY
ISSN journal
0148396X → ACNP
Volume
46
Issue
1
Year of publication
2000
Pages
218 - 221
Database
ISI
SICI code
0148-396X(200001)46:1<218:EAPRNT>2.0.ZU;2-1
Abstract
OBJECTIVE AND IMPORTANCE: Pregnancy-related vertebral hemangioma compressiv e myelopathy is a rare occurrence that tends to arise in the upper thoracic and lower cervical spine, peaks during the third trimester, and remits aft er parturition, Whether corticosteroid receptors play a role in the pathoge nesis of these lesions is unknown. Most of these lesions have been managed with posterior decompression CLINICAL PRESENTATION: A 29-year-old woman presented with acute-onset lower -extremity weakness and sensory loss immediately after parturition. INTERVENTION: We used a retropleural approach for anterior decompression an d fusion, followed by radiation therapy. Immunohistochemical analysis of es trogen and progesterone receptor expression was performed. CONCLUSION: We report an unusual case of lower thoracic postpartum vertebra l hemangioma compressive myelopathy caused by a parturition-related compres sion fracture. Results of tests for corticosteroid receptors were negative, which implicated a hemodynamic rather than hormonal cause for disease prog ression.