Th. Schwartz et al., Estrogen and progesterone receptor negative T11 vertebral hemangioma presenting as a postpartum compression fracture: Case report and management, NEUROSURGER, 46(1), 2000, pp. 218-221
OBJECTIVE AND IMPORTANCE: Pregnancy-related vertebral hemangioma compressiv
e myelopathy is a rare occurrence that tends to arise in the upper thoracic
and lower cervical spine, peaks during the third trimester, and remits aft
er parturition, Whether corticosteroid receptors play a role in the pathoge
nesis of these lesions is unknown. Most of these lesions have been managed
with posterior decompression
CLINICAL PRESENTATION: A 29-year-old woman presented with acute-onset lower
-extremity weakness and sensory loss immediately after parturition.
INTERVENTION: We used a retropleural approach for anterior decompression an
d fusion, followed by radiation therapy. Immunohistochemical analysis of es
trogen and progesterone receptor expression was performed.
CONCLUSION: We report an unusual case of lower thoracic postpartum vertebra
l hemangioma compressive myelopathy caused by a parturition-related compres
sion fracture. Results of tests for corticosteroid receptors were negative,
which implicated a hemodynamic rather than hormonal cause for disease prog
ression.