E. Belsito et al., Straightforward synthesis of lupophilic thymidine glucopyranosyl monophosphates as models for a drug delivery system across cellular membranes, NUCLEOS NUC, 18(11-12), 1999, pp. 2565-2580
O-methyl (3'-6) and (5'-6) thymidinyl gluco- and mannopyranosides and (3'-6
) thymidinyl glucofuranose can be synthesised in excellent yields by applyi
ng the phosphotriester method. The lipophilic phosphotriesters thus obtaine
d are designed as carriers of nucleoside drugs across cellular membranes.