BACKGROUND: We report here the first adult case of combined liver-small bow
el transplantation performed in France.
CASE REPORT: A double liver + small bowel graft was transplanted in a 21-ye
ar-old patient hospitalized for 4 years for a short bowel syndrome requirin
g total parenteral nutrition. The patient also had severe hepatic fibrosis.
The immediate post-operative period was uneventful. Two and one-half years
after the double graft, the patient is on strictly oral nutrition, no long
er has a stomy and lives a normal life in his home.
DISCUSSION: The advent of tacrolimus has led to long-term success of bowel
grafts, developed earlier in children and now possible in adults. Combined
liver-small bowel transplantation is formally indicated in patients with ci
rrhogenic liver disease associated with irreversible small bowel failure.