V. Wenzel et al., Effects of smaller tidal volumes during basic life support ventilation in patients with respiratory arrest: good ventilation, less risk?, RESUSCITAT, 43(1), 1999, pp. 25-29
Objective: When ventilating an unintubated patient in cardiac or respirator
y arrest, smaller tidal volumes of 500 mi instead of 800-1200 ml may be ben
eficial to decrease peak airway pressure, and to minimise stomach inflation
. The purpose was to determine the effects of small (similar to 500 ml) ver
sus large (similar to 1000 mi) tidal volumes given with paediatric versus a
dult self-inflatable bags and similar to 50% oxygen on respiratory paramete
rs in patients during simulated basic life support ventilation. Methods: Wh
ile undergoing induction of anaesthesia, patients were randomised to three
minutes of ventilation with either an adult (n = 40) or paediatric (n = 40)
self-inflatable bag. Results: When compared with an adult self-inflatable
bag, the paediatric bag resulted in significantly lower mean (+/- standard
deviation) exhaled tidal volume (365 +/- 55 versus 779 +/- 122 mi, P < 0.00
01), peak airway pressure (20 +/- 2 versus 25 +/- 5 cm H2O; P < 0.0001), bu
t comparable oxygen saturation (97 +/- 1% versus 98 +/- 1%; NS (nonsignific
ant)). Stomach inflation occurred in five of 40 patients ventilated with an
adult self-inflatable bag, but in no patients who were ventilated with a p
aediatric self-inflatable bag (P = 0.054). Conclusion: Administering smalle
r tidal volumes with a paediatric instead of an adult self-inflatable bag i
n unintubated adult patients with respiratory arrest maintains good oxygena
tion and carbon dioxide elimination while decreasing peak airway pressure,
which makes stomach inflation less likely. (C) 1999 Elsevier Science Irelan
d Ltd. All rights reserved.