EFFECTS OF AN INGESTED GLUTAMATE ARGININE SALT ON AMMONEMIA DURING AND AFTER LONG-LASTING CYCLING

The purpose of this study was to examine the effect of glutamate-argin ine salt (AGs) or placebo (P 1) on ammonemia during and after 1 hour e xercise on sporting event bicycle under ergonomic device at 80% VO2max in 3 healthy male volunteers (age 18 - 25 years). Subjects were teste d in three sessions, at rest after AGs and during exercise with placeb o (P1) or AGs. The subjects were given 20 g of AGs or P1 orally and 30 min later, exersised at 75-80% VO2max for 30 min. Blood samples were taken at 0, +;30, +60, +90, +120 min after AGs and analyzed for ammone mia. Our results show a highly significant increase in plasma ammonia concentration during exercise. The magnitude of this increase was dimi nished when subjects were given AGs before the exercise session, sugge sting that AGs may help reduce physiologic fatigue.