Recent reviews on musculoskeletal disorders have clearly pointed out the ne
ed for more good-quality original research. Both symptom-based and objectiv
e outcome assessment methods should be improved. A variety of methods exist
s to assess exposure for short-term, outcomes, whereas exposure assessment
strategies for outcomes with long induction times should be developed. The
change in exposure patterns - less force demands, more static, visual, cogn
itive, psychological and social load - will continue during the next millen
nium, and a likely result is a change in the disease panorama. The pathomec
hanisms of the effects of low-level static contractions and adverse psychos
ocial conditions need clarification. Genetic epidemiology is an emerging fi
eld of research, and it will be particularly interesting to study the inter
action between genetically determined susceptibility and occupational risk
factors. Because degeneration of the spine starts in adolescence, the impor
tance of studying the etiology of degenerative disorders among young popula
tions is emphasized.