Magnetic resonance imaging of intracranial plasmocytic granuloma

The objective of this study is to determine characteristic magnetic resonan ce imaging (MRI) features of intracranial plasmocytic granulomas, Pathologi cal confirmation of three patients with intracranial pathologically confirm ed plasmocytic granuloma die presented. Clinical records as well pre- and p ostgadolinium-enhanced images from each patient are reviewed. The location of the abnormalities is compared with previous reported cases of,, plasmocy tic granulomas, to determine if there;is a characteristic finding in this T he predominance of this abnormality in the pediatric and young adult patien t was striking. On T-1-weighted MRI, plasmocytic granulomas appear as hypoi ntense lesions, with isointense appearance on T-2 images, and significant, variable patterns of enhancement after the infusion of gadolinium. Typicall y, the lesion is infiltrating, and causes little mass effect. A dural based lesion, as well as a sellar region abnormality and an infiltrating cortica l lesion with little mass effect in the pediatric or young adult age group may Lead the observer to suspect the diagnosis of plasmocytic granuloma.