During the 1940s, in Britain, there was great activity in the field of soci
al medicine. This was generated by an upsurge in interest in social issues
and a desire to promote occupational health research. In 1948 the Medical R
esearch Council established a Social Medicine Research Unit. The background
to the creation of the Unit and its early work are discussed. By the early
1950s, the political atmosphere had changed and criticisms of the Unit's w
ork during the debate about continued funding in 1952 are considered. Impor
tant work on the relationship between coronary heart disease and physical e
xercise, and the results of a study of infant mortality, were published in
the mid-1950s. A brief account of the subsequent history of the Unit, until
its closure in 1975, is given.