A CASE OF AMIODARONE AND NEUROMYOPATHY

Citation
Es. Oropeza et al., A CASE OF AMIODARONE AND NEUROMYOPATHY, Revista de Investigacion Clinica, 49(2), 1997, pp. 135-139
Citations number
16
Categorie Soggetti
Medicine, General & Internal
ISSN journal
00348376
Volume
49
Issue
2
Year of publication
1997
Pages
135 - 139
Database
ISI
SICI code
0034-8376(1997)49:2<135:ACOAAN>2.0.ZU;2-H
Abstract
Amiodarone is a drug broadly used on cardiac arrhythmias despite its m ultiple side-effects. We present the case of an adult male with sympto matic ventricular tachycardia, receiving longterm amiodarone, who show ed increased CK serum levels, sensorymotor neuropathy and secondary my opathy. Cuadriceps biopsy showed atrophic changes and sural nerve intr alysosomal deposits with intense axonal degeneration. The case illustr ates the need to investigate and monitor peripheral neuropathy and mus cular atrophy in chronic amiodarone use.