Tj. Albert et al., Management of symptomatic lumbar pseudarthrosis with anteroposterior fusion - A functional and radiographic outcome study, SPINE, 25(1), 2000, pp. 123-129
Study Design. An independent retrospective review of 37 patients undergoing
39 anteroposterior lumbar fusions for lumbar pseudarthrosis repair between
1984 and 1990.
Objectives. To evaluate radiographically and functionally the results of th
e combined anteroposterior fusion for the management of symptomatic lumbar
pseudarthrosis, and to assess risk factors for functional failure after the
procedure.
Summary of Background Data. Most reported techniques of pseudarthrosis repa
ir involve posterior fusion with no instrumentation, posterior fusion with
instrumentation, OF anterior fusion alone. The results of lumbar pseudarthr
osis repair are poor. Fusion rates range from 30% to 70%, with only a 30% t
o 50% rate of functional success.
Methods. Thirty-nine procedures were assessed in 37 patients. The outcomes
were assessed radiographically (solid fusion vs. pseudarthrosis) and functi
onally (success vs. failure). Radiographs were assessed at follow-up examin
ation for consolidation of fusion anteriorly and posteriorly. Functional ou
tcome was graded by using multiple instruments, including data from chart r
eview and the follow-up outcome questionnaire. A functional failure score t
hat took into account 10 items was developed.
Results, In this patient population (37 patients, 59% with a smoking histor
y, 71% with compensation or legal claims), there was a 10% pseudarthrosis r
ate. Pseudarthrosis was defined when one or more levels were involved and w
hen it occurred anteriorly and posteriorly. In 12 patients (35%), the outco
me was rated as functional failure. The presence of one or more abnormal ne
urologic findings and significant narcotic use before surgery significantly
increased the chance of a patient's outcome being functional failure, Work
men's Compensation or legal status before surgery also increased the chance
of functional failure, though this correlation was not statistically signi
ficant.
Conclusions. A combined anterior and posterior approach for the management
of symptomatic lumbar pseudarthrosis is a viable alternative to posterior f
usion alone. In fact, this procedure affords a higher fusion rate based on
radiographic assessment. Functional failure rates may be decreased by using
caution for those patients using narcotics regularly before surgery or in
those with unexplained preoperative neurologic abnormal findings.