Mineralocorticoid action

The physiology of mineralocorticoid action, particularly with respect to ep ithelial sodium transport, is well defined. A full understanding of the mol ecular basis of mineralocorticoid action has however proven to be more elus ive. In the last decade insights into structural and functional aspects of the mineralocorticoid receptor combined with emerging details of the compon ents of the mediators of the sodium flux has resulted in a clearer picture. This review focuses on two aspects of these new developments; the mineralo corticoid receptor and putative aldosterone induced proteins. (C) 2000 Else vier Science Inc. All rights reserved.