K. Tsugawa et al., The effect of carbon dioxide pneumoperitoneum on the portal hemodynamics in a portal-hypertensive rat model, SURG LA E P, 9(5), 1999, pp. 338-347
As use of laparoscopic surgery grows, various complications with pneumoperi
toneum have been reported. However, there are no reports on the relation be
tween the carbon dioxide (Co-2) pneumoperitoneum and portal hemodynamics. T
he purpose of this study was to determine how the pneumoperitoneum affects
the portal hypertensive state. Portal-hypertensive rats, control rats, and
sham operation rats were studied. The mean arterial pressure, portal venous
pressure, central venous pressure, red blood flow volume of the viscera, a
nd liver and renal function were investigated. The findings of this study s
uggest that Co-2 pneumoperitoneum at less than 10 mm Hg does not present an
y undue risk to the portal hemodynamics in portal-hypertensive rats; howeve
r, more attention should be paid to the IAP in PHT patients undergoing surg
ery.