Synthesis of functional bisphosphonates via new palladium-catalyzed bis-hydrophosphorylation reactions

Authors
Allen, A Manke, DR Lin, WB
Citation
A. Allen et al., Synthesis of functional bisphosphonates via new palladium-catalyzed bis-hydrophosphorylation reactions, TETRAHEDR L, 41(2), 2000, pp. 151-154
Citations number
8
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
2
Year of publication
2000
Pages
151 - 154
Database
ISI
SICI code
0040-4039(20000108)41:2<151:SOFBVN>2.0.ZU;2-I
Abstract
A series of functional bisphosphonates have been synthesized in good isolat ed yields via new palladium-catalyzed bis-hydrophosphorylation reactions of terminal alkynes and dialkyl phosphites. The scope and mechanism for such a bis-hydrophosphorylation process are also discussed. (C) 1999 Elsevier Sc ience Ltd. All rights reserved.