A novel method for sequence independent incorporation of activated/protected cysteine in Fmoc solid phase peptide synthesis

Authors
Ghosh, AK Fan, E
Citation
Ak. Ghosh et E. Fan, A novel method for sequence independent incorporation of activated/protected cysteine in Fmoc solid phase peptide synthesis, TETRAHEDR L, 41(2), 2000, pp. 165-168
Citations number
8
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
2
Year of publication
2000
Pages
165 - 168
Database
ISI
SICI code
0040-4039(20000108)41:2<165:ANMFSI>2.0.ZU;2-V
Abstract
In conventional stepwise Fmoc solid phase peptide synthesis, incorporation of cysteine with nitro-pyridine sulfenyl (Npys) or pyridine sulfenyl (Pys) groups which act as an activation/protection of the thiol function has been accomplished in a sequence independent manner. (C) 1999 Elsevier Science L td. All rights reserved.