Electrochemical cross-coupling between functionalized aryl halides and 2-chloropyrimidine or 2-chloropyrazine catalyzed by nickel 2,2 '-bipyridine complex
C. Gosmini et al., Electrochemical cross-coupling between functionalized aryl halides and 2-chloropyrimidine or 2-chloropyrazine catalyzed by nickel 2,2 '-bipyridine complex, TETRAHEDR L, 41(2), 2000, pp. 201-203
2-Arylpyrimidines and 2-arylpyrazines have been obtained in good to high yi
elds from 2-chloropyrimidine and 2-chloropyrazine and various functionalize
d aryl halides by electroreduction using an iron rod as the anode and a cat
alytic amount of nickel-bipyridine complex in a mixture of DMF and pyridine
as solvent. (C) 1999 Elsevier Science Ltd. All rights reserved.