Infectious agents in systems for producing bovine embryos might reduce the
number and quality of embryos generated, result in transmission of disease
to recipients and offspring, or confound findings of research. Embryo-assoc
iated pathogens might also jeopardize human health when the goal of embryo
production is creating transgenic animals intended to be a source of pharma
ceuticals or organs. This paper addresses risks and resulting hazards of pa
thogen and microbial contaminant introduction into in vivo or in vitro embr
yo production systems. Additionally, methods for prevention and quality con
trol are discussed. (C) 1999 by Elsevier Science Inc.